It is a new quit smoking drug approved by the FDA under the name of Chantix in the United States and under the name of Champix in the European Union. Generic name of these drugs is Varenicline. Whether you buy Champix or Chantix, you get exactly the same medicine: Varenicline made by Pfizer.

Varenicline displays almost 100% absorption after oral administration and bioavailability doesn't depend of administration time or meals. The Primary mechanism of varenicline is clearance and renal elimination is 92% percent excreted unchanged in the urine. Estimated half-life after oral administration is 24 hours.

Initial studies report that using this drug more patients were able to achieve smoking cessation after 12 weeks. The most common adverse effect associated with varenicline is nausea.

In summary, varenicline is a partial agonist of the alpha-4 beta-2 nicotinic acetylcholine receptor approved as a quit smoking medicine. It increases the percent of patients able to achieve long-term abstinence compared to other drugs in this category or placebo.